| 小剂量^16O^8＋离子预辐射减轻大剂量辐射所致小鼠睾丸组织损伤 |
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| 引用本文： | 张红,张煦等兰.小剂量^16O^8＋离子预辐射减轻大剂量辐射所致小鼠睾丸组织损伤[J].实验生物学报,2000,33(2):97-100. |
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| 作者姓名： | 张红 张煦等兰 |
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| 作者单位： | [1]中国科学院近代物理研究所 [2]州医学院病理解剖教研室 |
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| 摘 要： |
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| 关 键 词： | ^16O^8＋离子 小剂量辐射 睾丸 适应性反应 小鼠 |
Alleviation of pre-exposure to low-dose 16O8+ ion on mouse testicular histological damage induced by subsequent high-dose irradiation. |
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| H Zhang,X Zhang,R L Zheng,Q X Gao,Z Q Wei,W J Li,W Q Chen,J P Liang,G W Han,T Huang,H M Xie.Alleviation of pre-exposure to low-dose 16O8+ ion on mouse testicular histological damage induced by subsequent high-dose irradiation.[J].Acta Biologiae Experimentalis Sinica,2000,33(2):97-100. |
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| Authors: | H Zhang X Zhang R L Zheng Q X Gao Z Q Wei W J Li W Q Chen J P Liang G W Han T Huang H M Xie |
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| Institution: | Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 |
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| Abstract: | The testes of the B6C3F1 hybrid strain mice were irradiated with 0.05 Gy of 16O8+ ion as the pre-exposure dose (D1), and were then irradiated with 2 Gy of 16O8+ ion as challenging radiation dose (D2) at 4 h after per-exposure. Testicular morphology was observed by light microscope at 35th day after radiation. The results showed that irradiation of mouse testes with 2 Gy of 16O8+ ion significantly impaired, mainly reduction of tubule diameter and decrease or loss of germ cells in various developing stages, especially spermatogenic elements. Pre-exposure to a low-dose (0.05 Gy) of 16O8+ ion significantly alleviated above mentioned damage on testicular morphology induced by subsequent a high-dose (2 Gy) radiation. |
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