Effect of Ocimum sanctum fixed oil on vascular permeability and leucocytes migration |
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Authors: | Singh S Majumdar D K |
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Institution: | College of Pharmacy (University of Delhi), New Delhi, India. |
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Abstract: | Ocimum sanctum fixed oil significantly inhibited the rise in protein concentration and dye leakage in peritoneal fluid in experimentally induced peritoneal inflammation in mice. In carrageenan-induced pleurisy in rats, the fixed oil showed significant inhibition of leucocytes migration in the pleural exudate. The results suggest that the fixed oil can inhibit enhancement of the vascular/capillary permability and leucocyte migration following inflammatory stimulus. |
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