Three antinematodal diterpenes from Euphorbia kansui |
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| Authors: | Shi Jian-Xiao Li Zhi-Xuan Nitoda Teruhiko Izumi Minoru Kanzaki Hiroshi Baba Naomichi Kawazu Kazuyoshi Nakajima Shuhei |
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| Affiliation: | The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University, Okayama, Japan. |
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| Abstract: | Three compounds, 20-O-acetyl-[3-O-(2'E,4'Z)-decadienoyl]-ingenol (1), 20-O-acetyl-[5-O-(2'E,4'Z)-decadienoyl]-ingenol (2) and 3-O-(2'E,4'Z)-decadienoylingenol (3), were isolated from Euphorbia kansui under the bioassay-guided method. Each compound showed the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball. |
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