Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1 |
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| Authors: | M Mehrabian R S Sparkes T Mohandas A M Fogelman A J Lusis |
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| Affiliation: | Division of Cardiology, University of California, Los Angeles 90024. |
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| Abstract: | ![]()
Monocyte chemotactic protein-1 (MCP-1) is a member of the small inducible gene (SIG) family. It has been shown to play a role in the recruitment of monocytes to sites of injury and infection. By analysis of a panel of somatic cell hybrids, we have localized the MCP-1 gene, designated SCYA2, to human chromosome 17. In situ hybridization confirmed this assignment and further localized the gene to 17q11.2-q21.1. |
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