Cardiogenic reflexes after immune injury of the heart |
| |
Authors: | V B Pavlyuchenko A A Moibenko L V Tumanovskaya |
| |
Institution: | (1) Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine |
| |
Abstract: | Afferent and efferent spike activity from the parasympathetic (vagus) and sympathetic cardiac nerves were recorded simultaneously with ECG, and indices of heart function were measured in acute experiments on anesthetized dogs, which allowed us to study the modifications of cardio-cardiac reflex influences after a local immune heart injury. After an injury nidus has been formed in the heart, cardiogenic depressor reflexes evoked by an intracoronary application of veratrine or bradykinin were considerably suppressed or even abolished, and afferent spike activity in the vagus cardiac nerves noticeably decreased. At the same time, both the facilitation of activity in sympathetic afferent fibers and pressor reflex effects were preserved after the heart injury. Different localization of vagus and sympathetic afferent structures in the heart and their specialized sensitivity to the biologically active substances are suggested as the factors determining the pattern of cardiogenic reflex influences after a heart injury.Neirofiziologiya/Neurophysiology, Vol. 27, No. 1, pp. 18–25, January–February, 1995. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|