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Intracellular Transfer of Na+ in an Active-State G-Protein-Coupled Receptor
Authors:Owen N Vickery  Catarina A Carvalheda  Saheem A Zaidi  Andrei V Pisliakov  Vsevolod Katritch  Ulrich Zachariae
Institution:1. School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK;2. School of Science and Engineering, University of Dundee, Dundee DD1 4NH, UK;3. Department of Biological Sciences, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA;4. Department of Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA 90089, USA
Abstract:
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  • Keywords:GPCR activation  polar network  free energy profiles  ion channels  protonation state  signal transduction  GPCR  membrane surface receptors  sodium
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