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Metabolomics standards initiative: ontology working group work in progress |
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| Authors: | Susanna-Assunta Sansone Daniel Schober Helen J. Atherton Oliver Fiehn Helen Jenkins Philippe Rocca-Serra Denis V. Rubtsov Irena Spasic Larisa Soldatova Chris Taylor Andy Tseng Mark R. Viant |
| Affiliation: | (1) EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK;(2) European Nutrigenomics Organization (NuGO), Norwich, England;(3) Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, UK;(4) UC Davis Genome Center, 5, 451 East Health Sciences Drive, Davis, CA 95616-8816, USA;(5) Department of Computer Science, University of Wales, Penglais, Aberystwyth, Ceredigion, Wales, SY23 3DB, UK;(6) School of Computer Science, Manchester Centre for Integrative Systems Biology, Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK;(7) Manchester Interdisciplinary Biocentre, 131 Princess Street, Manchester, M17DN, UK;(8) Bioanalytical Sciences Group, School of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK;(9) School of Biosciences, The University of Birmingham, Birmingham, B15 2TT, UK |
| Abstract: | In this article we present the activities of the Ontology Working Group (OWG) under the Metabolomics Standards Initiative (MSI) umbrella. Our endeavour aims to synergise the work of several communities, where independent activities are underway to develop terminologies and databases for metabolomics investigations. We have joined forces to rise to the challenges associated with interpreting and integrating experimental process and data across disparate sources (software and databases, private and public). Our focus is to support the activities of the other MSI working groups by developing a common semantic framework to enable metabolomics-user communities to consistently annotate the experimental process and to enable meaningful exchange of datasets. Our work is accessible via a public webpage and a draft ontology has been posted under the Open Biological Ontology umbrella. At the very outset, we have agreed to minimize duplications across omics domains through extensive liaisons with other communities under the OBO Foundry. This is work in progress and we welcome new participants willing to volunteer their time and expertise to this open effort. See the MSI Ontology Working Group website for a complete list of members and contributors. Web URL: |
| Keywords: | Controlled vocabulary Annotation Terminology Semantic Metadata Ontology Functional genomics Metabolomics Metabonomics Standard Metabolomics society Metabolomics standards initiative OBO |
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