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Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid |
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| Authors: | Yamauchi Satoshi Masuda Toshiya Sugahara Takuya Kawaguchi Yuya Ohuchi Maya Someya Tatsushi Akiyama Jun Tominaga Shiori Yamawaki Manami Kishida Taro Akiyama Koichi Maruyama Masafumi |
| Affiliation: | Faculty of Agriculture, Ehime University, Japan. |
| Abstract: | The antioxidant activity of butane-type lignans was evaluated. Secoisolariciresinol (SECO) and dihydroguaiaretic acid (DGA) showed higher radical scavenging activity than that of 7,7'-dioxodihydroguaiaretic acid (ODGA). SECO and DGA inhibited the oxidation of unsaturated fatty acid. Both enantiomers of DGA were also lipoxygenase inhibitors, but neither enantiomer of SECO inhibited the lipoxygenase activity. |
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