Secretory granules of prolactin cells of neonatally thyroidectomized female rats |
| |
| Authors: | Dr Masataka Shiino Koh-en Yamauchi |
| |
| Institution: | (1) Department of Anatomy, Wakayama Medical College, Wakayama, Japan;(2) Department of Anatomy, Wakayama Medical College, 9-Kyubancho, 640 Wakayamashi, Japan |
| |
| Abstract: | In the anterior pituitary glands of neonatally thyroidectomized female rats sacrificed at 30 days of age, the prolactin granules were small and spherical in shape. The administration of thyroxine to neonatally thyroidectomized rats produced an obvious increase in the number and size of secretory granules in prolactin cells; comparatively large, pleomorphic secretory granules were frequently observed in these cells. These enlarged and pleomorphic granules closely resembled those observed in the prolactin cells of sham-operated control rats. These results may indicate that thyroxine stimulates the basic metabolism or cellular function of prolactin cells of neonatally thyroidectomized rats and leads to the formation of prolactin granules that are similar to those of sham-operated control rats. |
| |
| Keywords: | Pituitary gland pars anterior Prolactin cells Secretory granules Thyroxine Thyroidectomy Rat |
| 本文献已被 SpringerLink 等数据库收录！ |
|
