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The discovery and development of microbial bleomycin analogues |
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| Authors: | Kong Jieqian Yi Liwei Xiong Yi Huang Yong Yang Dong Yan Xiaohui Shen Ben Duan Yanwen Zhu Xiangcheng |
| Affiliation: | 1.Xiangya International Academy of Translational Medicine, Central South University, Tongzipo Road, #172, Yuelu District, Changsha, 410013, Hunan, China ;2.National Engineering Research Center of Combinatorial Biosynthesis for Drug Discovery, Changsha, 410013, Hunan, China ;3.Department of Chemistry, The Scripps Research Institute, Jupiter, FL, 33458, USA ;4.Natural Products Library Initiative at The Scripps Research Institute, The Scripps Research Institute, Jupiter, FL, 33458, USA ;5.Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA ;6.Hunan Engineering Research Center of Combinatorial Biosynthesis and Natural Product Drug Discovery, Changsha, 410013, Hunan, China ; |
| Abstract: | Applied Microbiology and Biotechnology - The bleomycins (BLMs) belong to a subfamily of glycopeptide antibiotics and are clinically applied in combination chemotherapy regimens to treat various... |
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