Matrix gamma-carboxyglutamic acid protein (MGP) G-7A and T-138C gene polymorphisms in Indian (Mayo and Teenek) and Mestizo populations from Mexico |
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| Authors: | Hernández-Pacheco Guadalupe Murguía Luis Enrique Rodríguez-Pérez José Manuel Fragoso José Manuel Pérez-Vielma Nadia Martínez-Rodríguez Nancy Granados Julio Vargas-Alarcón Gilberto |
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| Affiliation: | Department of Physiology and Grupo de Estudio en Genómica y Proteómica de Enfermedades Cardiovasculares, Instituto Nacional de Cardiología "Ignacio Chávez," Juan Badiano No. 1, Tlalpan 14080, Mexico City, Mexico. |
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| Abstract: | ![]()
Matrix gamma-carboxyglutamic acid protein (MGP) genotypes (G-7A and T-138C) were determined in 266 individuals from three Mexican populations. Mexicans showed increased frequencies of the G-7A G allele and the G7-A GG genotype compared to Europeans. For the T-138C genotype, we found differences among the Mexicans. This study could help to define the significance of MGP polymorphisms as genetic markers in Amerindian populations. |
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