A genetic and physical map of bovine Chromosome 11 |
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| Authors: | D Vaiman D Mercier A Eggen I Bahri-Darwich C Grohs E P Cribiu G Dolf A Oustry G Guérin H Levéziel |
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| Institution: | (1) Laboratoire de Génétique biochimique et de Cytogénétique, INRA-CRJ, Domaine de Vilvert, 78350 Jouy-en-Josas Cedex, France;(2) Institute of Animal Breeding, University of Berne, Bremgartenstrasse 109a, CH-3012 Berne, Switzerland |
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| Abstract: | A genetic map of bovine Chromosome (Chr) 11 (BTA11, synteny group U16) has been constructed from 330 animals belonging to 21 families, which constitute the international bovine reference panel (IBRP). This map is based on 13 polymorphic microsatellite markers, two of which were chosen in previously published maps. Three markers have been isolated from cosmids. Two of the three cosmids have been physically localized by fluorescence in situ hybridization (FISH), to anchor the genetic map on the chromosome. In addition, a biallelic polymorphism in the  -lactoglobulin gene (LGB) has been genetically positioned relative to the microsatellite markers. The most probable order of the markers is: cen-INRA044-BM716-INRA177-(TGLA 327, INRA198, INRA131)-INRA111-INRABERN169-(INRA115, INRA032)-INRA108-INRABERN162-INRA195-LGB. T The total linkage group spans 126 cM, which probably corresponds to most of the chromosome length. The average intermarker distance is about 10.5 cM, allowing the potential detection of a genetic linkage with any Economic Trait Loci (ETL) of this chromosome. |
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