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ent-Labdane diterpenes from the aquatic plant Potamogeton pectinatus
Authors:Waridel Patrice  Wolfender Jean-Luc  Lachavanne Jean-Bernard  Hostettmann Kurt
Institution:Institut de Pharmacognosie et Phytochimie, Université de Lausanne, CH-1015 Lausanne, Switzerland.
Abstract:Four new ent-labdane diterpenes were isolated from the freshwater aquatic plant Potamogeton pectinatus, together with two known furano-ent-labdanes. The new compounds were assigned the structures methyl-15,16-epoxy-12(R)-acetoxy- 8(17), 13(16),14-ent-labdatrien-19-oate,15,16-epoxy-12(R)-acetoxy-8(17), 13(16),14-ent-labdatrien-19-oic acid, 8(17),13-ent-labdadien-15 --> 16-lactone-19-oic acid and 16-hydroxy-8(17),13-ent-labdadien-15,16-olid-19-oic acid by spectroscopic means. Some of these labdanes showed a strong algicidal activity against Raphidocelis subcapitata.
Keywords:Potamogeton pectinatus  Potamogetonaceae  Spectroscopic analysis  LC-MS  LC-NMR  ent-Labdane diterpenes  Antialgal activity
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