Assignment by in situ hybridization of a fibroblast growth factor receptor gene to human chromosome band 10q26 |
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| Authors: | Marie-Geneviève Mattei Agnès Moreau Marie-Claude Gesnel Elisabeth Houssaint Richard Breathnach |
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| Institution: | (1) INSERM Unité 242, Hôpital d'Enfants, Groupe Hospitalier de la Timone, F-13385 Marseille Cedex 5, France;(2) INSERM Unité 211 and Faculté des Sciences et des Techniques, Faculté de Médecine, Université de Nantes, 1, Rue Gaston Veil, F-44035 Nantes Cedex, France;(3) INSERM Unité 211, Faculté de Médecine, Université de Nantes, 1, Rue Gaston Veil, F-44035 Nantes Cédex, France |
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| Abstract: | Summary A 2.3-kb cDNA probe for the human bek fibroblast growth factor receptor was used to determine the chromosomal localization of the corresponding gene by in situ hybridization. The results show that this gene, a form of which is amplified in some poorly differentiated stomach cancers, is localized on chromosome region 10q26. The two previously identified fibroblast growth factor receptor genes are thus not on the same chromosome, as the related fig ( fms-like gene ) fibrovblast growth factor receptor gene has previously been mapped to human chromosome region 8p12. |
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