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Amyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line |
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| Authors: | Sung Hye Youn Choi Eun Nam Ahn Jo Sangmee Oh Seikwan Ahn Jung-Hyuck |
| Institution: | aDepartment of Biochemistry, School of Medicine, Ewha Womans University, 911-1 Mok-6-dong, Yangcheon-ku, Seoul 158-710, Republic of Korea;bDepartment of Neuroscience and TIDRC, School of Medicine, Ewha Womans University, 911-1 Mok-6-dong, Yangcheon-ku, Seoul 158-710, Republic of Korea;cDepartment of Pharmacy, College of Pharmacy, Dankook University, San 29 Anseo-dong, Dongnam-gu, Cheonan-si, Chungnam 330-714, Republic of Korea |
| Abstract: | |
| Keywords: | Abbreviations: 5-aza-dC 5-aza-2&prime -deoxycytidine Aβ beta amyloid AD Alzheimer&rsquo s disease APP amyloid precursor protein APP-sw Swedish mutation of amyloid precursor protein DMS differentially methylated CpG site MSP methylation-specific PCR qRT-PCR quantitative real-time polymerase chain reaction BSP bisulfite sequencing PCR CTIF CBP80/CBP20-dependent translation initiation factor NXT2 nuclear exporting factor 2 DDR discoidin domain receptor NBS Nijmegen breakage syndrome protein |
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