The structure and evolution of the spider monkey delta-globin gene |
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Authors: | Spritz RA; Giebel LB |
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Institution: | Department of Medical Genetics and Pediatrics, University of Wisconsin-- Madison 53706. |
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Abstract: | We have isolated the delta-globin gene of the New-World spider monkey,
Ateles geoffroyi, and compared its nucleotide sequence with those of other
primate delta- and beta-globin genes. Among primate delta-globin genes, the
rate of nonsynonymous substitutions is much less than the rate of
synonymous substitutions. This suggests that primate delta- globin genes
may remain under evolutionary conservation, perhaps because hemoglobin A2
has an as yet unknown physiological importance.
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