Antigen-specific augmentation of delayed-type hypersensitivity by a humoral factor in the culture supernatant of immune spleen cells |
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| Authors: | A Yamada K Himeno Y Kumazawa K Nomoto |
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| Affiliation: | 1. Department of Immunology, Medical Institute of Bioregulation, Kyushu University, Maidashi, Fukuoka 812, Japan;2. Department of Immunology and Virology, School of Pharmaceutical Sciences, Kitasato University, Tokyo 108, Japan |
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| Abstract: | ![]()
Supernatants were harvested from a 24-hr culture of immune mouse spleen cells and erythrocyte antigens. Delayed footpad reactions to such heterologous erythrocytes were augmented antigen specifically when the supernatants were transferred a few hours before immunization of recipients. The augmentation factor(s) contained in the supernatants may exert its effect on the induction phase of delayed-type hypersensitivity. |
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| Keywords: | To whom all correspondence should be addressed. |
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