(1) Immunology Laboratory, Department of Research, Alfred I. duPont Hospital for Children, Wilmington, Delaware, USA;(2) Chief Executive of the Practice, Alfred I. duPont Hospital for Children, Wilmington, Delaware, USA
Abstract:
Background
We have previously reported that altered culture conditions (a broth media with shaking) could induce a strain of Helicobacter pylori to assume a long spiral morphology resembling that described for Helicobacter heilmannii. The present study was initiated to determine if other strains of H. pylori could be induced to assume that morphology and if doing so would alter the expression of immunodominant proteins.