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Synthesis and anti-HCV activity of a new 2'-deoxy-2'-fluoro-2'-C-methyl nucleoside analogue |
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| Authors: | Hu Weidong Wang Ping'an Song Chuanjun Pan Zhenliang Wang Qiang Guo Xiaohe Yu Xuejun Shen Zhenhua Wang Shuyang Chang Junbiao |
| Affiliation: | Department of Chemistry, Zhengzhou University, Zhengzhou, Henan Province, PR China. |
| Abstract: | 2'-Deoxy-2'-fluoro-2'-C-methyl nucleoside analogue 4 was designed and synthesized. Initial biological studies indicated that this compound showed promising activity against HCV replication. |
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