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EUROCarbDB: An open-access platform for glycoinformatics
Authors:von der Lieth Claus-Wilhelm  Freire Ana Ardá  Blank Dennis  Campbell Matthew P  Ceroni Alessio  Damerell David R  Dell Anne  Dwek Raymond A  Ernst Beat  Fogh Rasmus  Frank Martin  Geyer Hildegard  Geyer Rudolf  Harrison Mathew J  Henrick Kim  Herget Stefan  Hull William E  Ionides John  Joshi Hiren J  Kamerling Johannis P  Leeflang Bas R  Lütteke Thomas  Lundborg Magnus  Maass Kai  Merry Anthony  Ranzinger René  Rosen Jimmy  Royle Louise  Rudd Pauline M  Schloissnig Siegfried  Stenutz Roland  Vranken Wim F  Widmalm Göran  Haslam Stuart M
Affiliation:Core Facility, Molecular Structure Analysis, German Cancer Research Center, Heidelberg, Germany.
Abstract:The EUROCarbDB project is a design study for a technical framework, which provides sophisticated, freely accessible, open-source informatics tools and databases to support glycobiology and glycomic research. EUROCarbDB is a relational database containing glycan structures, their biological context and, when available, primary and interpreted analytical data from high-performance liquid chromatography, mass spectrometry and nuclear magnetic resonance experiments. Database content can be accessed via a web-based user interface. The database is complemented by a suite of glycoinformatics tools, specifically designed to assist the elucidation and submission of glycan structure and experimental data when used in conjunction with contemporary carbohydrate research workflows. All software tools and source code are licensed under the terms of the Lesser General Public License, and publicly contributed structures and data are freely accessible. The public test version of the web interface to the EUROCarbDB can be found at http://www.ebi.ac.uk/eurocarb.
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