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Enantioselective hydrolysis of (±)-chloramphenicol palmitate by hydrolases |
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| Authors: | Robert Chnevert Roxane Pouliot Patrick Bureau |
| Affiliation: | Départment de Chimie, Faculté des Sciences et de Génie, Université Laval Québec, Canada, G1K 7P4 |
| Abstract: | (±)-Chloramphenicol palmitate has been efficiently resolved by enantioselective hydrolysis in organic medium in the presence of Rhizopus sp. lipase affording the palmitate of RR-chloramphenicol and SS- chloramphenicol in high chemical and enantiomeric yields. |
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