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H2O2 resistance is linked to the degree of fatty acid unsaturation in Streptomyces coelicolor A3(2)
Authors:Jae-heon Kim  Moon-soo Shim  Seung-yeol Son
Affiliation:(1) Department of Microbiology College of Natural Sciences, Dan-kook University, Cheon-an, 330-714, South Korea;(2) Research Center for Molecular Microbiology, Seoul National University, Seoul, 151-742, South Korea
Abstract:In Streptomyces coelicolor A3(2), as the content of palmitoleic acid increased with decreasing growth temperature, H2O2 resistance decreased. Production of thiobarbituric acid-reactive substances upon H2O2 treatment was increased by supplementing unsaturated fatty acids. Therefore, the content of palmitoleic acid is a determining factor for the survival of Streptomyces coelicolor A3(2) subjected to H2O2 stress.
Keywords:fatty acids  H2O2 resistance  S. coelicolor A3(2)  temperature
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