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N端脑钠肽前体在心血管疾病中的研究进展
引用本文:翟蒙恩,狄守印,李书凯,时全星,李娟,王跃民,裴建明.N端脑钠肽前体在心血管疾病中的研究进展[J].生物磁学,2011(20):3984-3987.
作者姓名:翟蒙恩  狄守印  李书凯  时全星  李娟  王跃民  裴建明
作者单位:[1]第四军医大学口腔医学系学员16队,陕西西安710032 [2]第四军医大学生理学教研室,陕西西安710032
基金项目:国家自然科学基金(NO:30900535,30971060,30700345);国家重大新药创制项目(2009ZX09103.671)
摘    要:N端脑钠肽前体(NT-proBNP)为脑钠肽(BNP)生成过程中产生的无活性肽段残片,其与BNP等摩尔量分泌。近年来,NT-proBNP的检测在心血管领域的作用越来越得到国内外学者的关注。NT-proBNP在心血管疾病的诊断、预后、分级等方面都具有重要的价值。本文主要介绍NT-proBNP在心血管疾病中的研究进展。

关 键 词:NT-proBNP  心衰  左室肥厚  二尖瓣狭窄  急性冠脉综合征

Progress of NT-proBNP in Cardiovascular Diseases
ZHAI Meng-en,DI Shou-yin,LI Shu-kai,SHI Quan-xing,LI Juan,WANG Yue-min,PEI Jian-ming.Progress of NT-proBNP in Cardiovascular Diseases[J].Biomagnetism,2011(20):3984-3987.
Authors:ZHAI Meng-en  DI Shou-yin  LI Shu-kai  SHI Quan-xing  LI Juan  WANG Yue-min  PEI Jian-ming
Institution:1 Cadet Squadron 16, Department of Stomatology, Fourth Military Medical University, Xi'an 710032, China; 2 Department of Physiology, Fourth Military Medical University, Xi'an, 710032, China)
Abstract:The N-terminal pro-brain natriuretic peptide (NT-proBNP), as a non-active peptides fragment, which is generated during the formation of the brain natriuretic peptide (BNP), is equimolarly secreted with BNP. Recent years, examination of NT-proBNP in the cardiovascular diseases has gained more and more attentions. Great values have been identified about NT-proBNP on diagnosis, prognosis and classification of cardiovascular diseases. This review is mainly about the progress of NT-proBNP in cardiovascular diseases.
Keywords:NT-proBNP  Heart failure  Left ventricular hypertrophy  Mitral valve stenosis  Acute coronary syndrome
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