姜黄素与消化系统肿瘤的研究进展

姜黄素是一种疏水多酚，从姜黄中提取的姜黄磺胺类草药。半个世纪以来大量的研究表明姜黄素在体外及体内显示了各种诸如抗炎、细胞活素的释放、抗氧化、免疫调节、促进凋亡以及抗血管生成的特性。姜黄素同样也被证明是耐药性和放疗不敏感性的调解者。同样，在各种临床试验研究中证明了姜黄素抗肿瘤的作用，本文就姜黄素在消化系统肿瘤中的抗肿瘤机制做一综述。

Progress of the research on tumors of alimentary system

Cureumin, commonly called difemloyl methane, is a hydrophobic polyphenol derived from rhizome （turmeric） of the herb Curcuma longa. Extensive research over the last half century has revealed important functions of curcumin. In vitro and in vivo research has shown various activities, such as anti-inflammatory, cytokines release, antioxidant, immunomodulatory, enhancing of the apoptotic process, and anti-angiogenic properties. Curcumin has also been shown to be a mediator of chemo-resistance and radio-resistance.The present study demonstrates that cureumin exerts anti-cancer Effect. This article reviews the effect of curcumin on tumors of alimentary system.