| 松茸多糖抗辐射功能的初步研究 |
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| 引用本文： | 陈月月,李雪静,王宏芳,张秀芝,石明,李娟.松茸多糖抗辐射功能的初步研究[J].天然产物研究与开发,2006,18(6):989-990,998. |
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| 作者姓名： | 陈月月 李雪静 王宏芳 张秀芝 石明 李娟 |
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| 作者单位： | 吉林大学公共卫生学院,长春,130021 |
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| 摘 要： | 预防给予小鼠松茸多糖(PTM),测定小鼠在受到2 Gy X线照射后,脾和胸腺重量、T淋巴细胞转化能力、外周血中白细胞数和肝组织中SOD、CAT、GSH-Px活性及MDA含量的变化,结果显示PTM处理组小鼠的各项指标与辐射对照组比较均有显著性差别,提示PTM可促进机体自由基的清除,增加机体抗氧化能力,对辐射所致的免疫损伤有明显的保护作用。
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| 关 键 词： | 松茸多糖 抗辐射 自由基 |
| 文章编号： | 1001-6880（2006）06-0989-03 |
| 收稿时间： | 2006-07-18 |
| 修稿时间： | 2006-07-182006-08-21 |
Preliminary Study on the Radiation-prevention Function of Polysaccharides of Tricholoma matsutake |
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| CHEN Yue-yue,LI Xue-jing,WANG Hong-fang,ZHANG Xiu-zhi,SHI Ming,LI Juan.Preliminary Study on the Radiation-prevention Function of Polysaccharides of Tricholoma matsutake[J].Natural Product Research and Development,2006,18(6):989-990,998. |
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| Authors: | CHEN Yue-yue LI Xue-jing WANG Hong-fang ZHANG Xiu-zhi SHI Ming LI Juan |
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| Institution: | School of Pablic Health, Jilin University, Changchun 130021, China |
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| Abstract: | Mice were treated with polysaccharides of Tricholoma matsutake(PTM) in 7 days and all groups except NC groups were irradiated once with 2 Gy X-ray in 8th day,then,the activity of SOD,CAT and GSH-Px and the content of MDA in liver homogenate,index of spleen and thymus,transformation ability of T lymphocyte were observed after irradiation.Results indicated that there was a significant difference between PTM group and IC group.PTM has an obvious radioprotective effect on the ability of anti-oxidant and immune function of X-ray irradiated mice. |
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| Keywords: | polysaccharides of Tricholoma matsutake radioprotection free radicals |
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