Study of TLR3, TLR4, and TLR9 in prostate carcinomas and their association with biochemical recurrence |
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| Authors: | Salomé González-Reyes Jesús M Fernández Luis O González Alina Aguirre Aurelio Suárez José M González Safwan Escaff Francisco J Vizoso |
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| Institution: | 1.Servicio Urología,Hospital de Jove,Gijón,Spain;2.Unidad de Investigación,Hospital de Jove,Gijón,Spain;3.Servicio de Urología,Hospital Universitario Central de Asturias,Oviedo,Spain;4.Servicio de Cirugía General,Hospital de Jove,Gijón,Spain |
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| Abstract: | Background Toll-like receptors (TLRs) have garnered an extraordinary amount of interest in cancer research due to their role in tumor
progression. By activating the production of several biological factors, TLRs induce type I interferons and other cytokines,
which drive an inflammatory response and activate the adaptive immune system. The aim of this study was to investigate the
expression and clinical relevance of TLR3, 4, and 9 in prostate cancer. |
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