| 趋化因子及其受体对血管内皮细胞的作用 |
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| 引用本文： | 肖艳辉,陆培荣.趋化因子及其受体对血管内皮细胞的作用[J].现代生物医学进展,2013,13(14):2790-2793. |
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| 作者姓名： | 肖艳辉 陆培荣 |
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| 作者单位： | 苏州大学附属第一医院眼科 江苏苏州215006 |
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| 基金项目： | 国家自然科学基金面上项目，江苏省医学重点人才项目 |
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| 摘 要： | 趋化因子是机体内一类重要的生物活性物质,参与多种生理病理活动的调控。趋化因子可通过对血管内皮细胞的趋化作用,引起血管内皮细胞增殖、迁移、毛细血管形成而促进血管生成;部分趋化因子可通过凋亡和抑制多种促血管生成因子的活性而发挥抑制血管生成的作用。现将趋化因子及其受体对血管内皮细胞的作用进行综述。
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| 关 键 词： | 趋化因子 受体 新生血管 内皮细胞 |
The Rrole of Chemokine and Chemokine Receptor on the Vascular Endothelial Cells |
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| XIAO Yan-hui,LU Pei-rong.The Rrole of Chemokine and Chemokine Receptor on the Vascular Endothelial Cells[J].Progress in Modern Biomedicine,2013,13(14):2790-2793. |
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| Authors: | XIAO Yan-hui LU Pei-rong |
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| Institution: | (Department of Ophthalmology,the First Affiliated Hospital of Soochow University,Jiangsu,Suzhou,215006,China) |
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| Abstract: | Chemokine,which is contained in regulating the physiological and pathological process,is an important cytokine.Chemokine and chemokine receptor play critical roles in neovascularization by inducing chemotaxis,proliferation,migration and tube formation of endothelial cells.Some chemokines can reduce neovascularization by inducing apoptosis and inhibiting angiogenic factors.We herein provide a summary of the roles of chemokine and chemokine receptor on the vascular endothelial cells. |
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| Keywords: | Chemokine Receptor Neovascularization Vascular endothelial cell |
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