The anti-cyclic citrullinated peptide response in tuberculosis patients is not citrulline-dependent and sensitive to treatment期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

The anti-cyclic citrullinated peptide response in tuberculosis patients is not citrulline-dependent and sensitive to treatment

Authors:	Ori Elkayam Refael Segal Daniele Bendayan Robert van Uitert Carla Onnekink Ger JM Pruijn

Affiliation:	(1) Department of Internal Medicine F and the Department of Rheumatology, Tel Aviv Medical Center and The "Sackler" Faculty of Medicine, Tel Aviv University, 6 Weizman Street, Tel Aviv, 64239, Israel;(2) Department of Geriatrics, Shmuel-Harofeh Geriatric Medical Centre and the "Sackler" Faculty of Medicine, University of Tel Aviv, POB 2, Beer Yaakov, 70300, Israel;(3) Department of Tuberculosis, Shmuel-Harofeh Geriatric Medical Center and the "Sackler" Faculty of Medicine, University of Tel Aviv, POB 2, Beer Yaakov, 70300, Israel;(4) Euro-Diagnostica AB, Beijerinckweg 18, 6827 BN, NL, Arnhem, The Netherlands;(5) Department of Biomolecular Chemistry, Nijmegen Center for Molecular Life Sciences, Institute for Molecules and Materials, Radboud University Nijmegen, NL, 6500 HB Nijmegen, The Netherlands

Abstract:	Introduction Patients with tuberculosis (TB) frequently produce anti-citrullinated protein antibodies (ACPA). The objective of this study is to characterize the citrulline-dependence of the ACPA reactivity in sera of patients with mycobacterium infections.

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