| 布鲁菌病的生物安全及防控 |
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| 引用本文： | 胡高维,陈明亮,蔡霞,瞿涤.布鲁菌病的生物安全及防控[J].微生物与感染,2022,17(2):118-122. |
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| 作者姓名： | 胡高维 陈明亮 蔡霞 瞿涤 |
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| 作者单位： | 1. 复旦大学三级生物安全防护实验室，复旦大学基础医学院病原生物学系，教育部/卫健委/中国医科院医学分子病毒学重点实验室，上海市重大传染病和生物安全研究院，上海200032; 2. 上海市疾病预防控制中心病原生物检定所，上海 200336 |
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| 基金项目： | “十三五”国家科技重大专项(2018ZX10734401) |
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| 摘 要： | 布鲁菌病(brucellosis)是布鲁菌入侵机体引起的传染-变态反应性人兽共患传染病，易被忽视。该病严重威胁人类健康，影响畜牧业、旅游业的发展，阻碍正常国际贸易，还会造成食品安全隐患。布鲁菌可通过消化道、呼吸道及皮肤黏膜破损处等途径传播至人。人群对布鲁菌的易感性无年龄和性别差异，可通过直接或间接接触感染。从事布鲁氏菌研究的实验室操作人员有发生实验室获得性感染的风险，但可通过有效的生物安全防护措施避免感染的发生。布鲁菌病是一种可防可控的疾病，必须早期诊断和正确治疗，防止疾病慢性化。本文对布鲁菌病的生物安全及其防控原则进行介绍。
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| 关 键 词： | 布鲁菌病 实验室获得性感染 生物安全 预防控制 |
Biosafety,prevention and control of brucellosis |
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| HU Gaowei,CHEN Mingliang,CAI Xia,QU Di.Biosafety,prevention and control of brucellosis[J].Journal of Microbes and Infection,2022,17(2):118-122. |
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| Authors: | HU Gaowei CHEN Mingliang CAI Xia QU Di |
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| Institution: | 1. Biosafety Level 3 Laboratory, Department of Medical Microbiology and Parasitology, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai Institute of Infectious Diseases and Biosecurity, Shanghai 200032, China; 2. Division of Microbiology, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China |
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| Abstract: | Brucellosis is an infectious-allergic zoonotic disease caused by Brucella. It is easily neglected. This disease seriously threatens human health, affects the development of animal husbandry and tourism, hampers normal international trade, and will cause hidden food safety hazards. Brucella can be transmitted to humans through multiple ways, including gastro-enteral tract, respiratory tract, and damaged skin and mucous membranes. There is no age or gender difference in the susceptibility of humans to Brucella. Humans can be infected with Brucella through direct or indirect contact. Laboratory-acquired brucellosis also occurs in laboratories dealing with Brucella, but it can be prevented with effective biosafety measures. Brucellosis is a preventable and controllable disease. It needs early diagnosis and proper treatment for preventing from chronic brucellosis. This review introduces the biosafety, prevention and control of brucellosis. |
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| Keywords: | Brucellosis Laboratory-acquired infection Biosafety Prevention and control |
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