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Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice |
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| Affiliation: | 1. Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA;2. Biological Physics, Structure and Design Graduate Program, University of Washington, Seattle, WA 98195, USA;3. Department of Microbiology, University of Washington, Seattle, WA 98195, USA;4. Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA |
| Abstract: |  |
| Keywords: | HIV Env glycoprotein HIV assembly Gag-Env interaction cryo-electron tomography sub-tomogram averaging hydrogen/deuterium-exchange mass spectrometry broadly neutralizing antibody cryo-electron microscopy virus structure vaccine design |
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