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用于肿瘤标志物检测的电化学免疫传感器
引用本文:陈钰,刘仲明,王捷.用于肿瘤标志物检测的电化学免疫传感器[J].生物磁学,2009(16):3166-3168,3197.
作者姓名:陈钰  刘仲明  王捷
作者单位:[1]广州军区广州总医院医学实验科,广东广州510010 [2]华南理工大学生物科学与工程学院,广东广州510006
基金项目:基金项目:2006年广东省自然科学基金重点项目“骨唾液蛋白在乳腺癌亲骨转移中的作用”(编号:06104396)
摘    要:联合检测几种肿瘤标志物,在肿瘤早期诊断中具有重要的临床应用价值。随着纳米技术、流动注射分析技术、微流控技术以及丝网印刷术的迅猛发展,电化学免疫传感器可以在肿瘤标志物的检测中扮演越来越重要的角色。本文主要介绍了电化学免疫传感器的原理及其在肿瘤蛋白标志物检测中的应用情况,并介绍了纳米材料、流动注射分析、微流控等技术在肿瘤标志物免疫传感器中的运用,展望了电化学免疫传感器的前景。

关 键 词:肿瘤标志物  电化学免疫传感器  检测

Electrochemical Immunosensor for Tumor Markers Detection
CHEN Yu LIU Zhong-ming,WANG Jie.Electrochemical Immunosensor for Tumor Markers Detection[J].Biomagnetism,2009(16):3166-3168,3197.
Authors:CHEN Yu LIU Zhong-ming  WANG Jie
Institution:1 Dept. Of Medical Research, General Hospital of Ouangzhou Command, Guangzhou 510010, China; 2 Coil. of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China )
Abstract:During the early diagnosis of tumor, it's valuable to detect several tumor marker. With rapid development of nanotechnology, flow injection analysis, microfluidics and Screen-printing technology, electrochemical immunosensors play more and more important role in detection of tumor marker and the early diagnosis of cancer. This review provides an introduce of the current focused tumor markers. It covers the basic principles and applications of electrochemical immunosensors. It also focuses on the application of nanotechnology, flow injection analysis, microfluidics and Screen-printing technology in electrochemical immunosensors to detect of tumor marker, and indicates the future prospects in this field.
Keywords:Tumor marker  Electrochemical immunosensor  Detection
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