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干细胞在胰腺癌中的研究进展
引用本文:刘俊,裘正军,庄瑜,钟福全. 干细胞在胰腺癌中的研究进展[J]. 生物磁学, 2009, 0(14): 2752-2755
作者姓名:刘俊  裘正军  庄瑜  钟福全
作者单位:上海交通大学医学院、上海交通大学附属第一人民医院,上海200080
摘    要:
胰腺癌是预后程度极差的恶性肿瘤,已初步证实胰腺干细胞可转化为胰腺癌细胞。成功分离和鉴定了胰腺癌干细胞并对其与转移、耐药的关系和信号通路异常的关系进行了初步研究。深入理解干细胞在胰腺癌中的作用,可能根本改变临床胰腺癌防治的方式。

关 键 词:干细胞  胰腺干细胞  胰腺癌干细胞  胰腺癌

Research Advancement of Stem Cell on Pancreatic Carcinoma
LIU Jun,QIU Zheng-jun,ZHUANG Yu,ZHONG Fu-quan. Research Advancement of Stem Cell on Pancreatic Carcinoma[J]. Biomagnetism, 2009, 0(14): 2752-2755
Authors:LIU Jun  QIU Zheng-jun  ZHUANG Yu  ZHONG Fu-quan
Affiliation:(Shanghai Jiaotong University School of Medicing Shanghai Jiaotong University Affiliated First People's Hospital,Shanghai20080, China )
Abstract:
Pancreatic carcinoma is a malignancy with extreme poor prognosis, and pancreatic stem cell has been demonstrated to be able to transform into pancreatic cancer cell. The pancreatic cancer stem cell were successfully isolated and identified a few years ago. The relationships of pancreatic cancer stem cell with metastasis, therapeutic resistance and abnormal signal pathway were investigated. A better understanding of the roles of stem cell on pancreatic carcinoma may ultimately change the prevention and therapy strategy of pancreatic carcinoma.
Keywords:Stem cell  Pancreatic stem cell  Pancreatic cancer stem cell  Pancreatic carcinoma
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