NF-κB transcription factors: critical regulators of hematopoiesis and neuronal survival

The Rel/NF-κB family of transcription factors has been implicated in the regulation of genes involved in immune and inflammatory responses, and of processes such as cell survival, apoptosis, development, differentiation, cell growth and neoplastic transformation. In this report we will summarize recent findings which highlight critical roles of NF-κB in different processes in hematopoietic and neuronal cells.