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Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs
Authors:Agata P Zielinska  Eirini Bellou  Ninadini Sharma  Ann-Sophie Frombach  K Bianka Seres  Jennifer R Gruhn  Martyn Blayney  Heike Eckel  Rüdiger Moltrecht  Kay Elder  Eva R Hoffmann  Melina Schuh
Institution:1. Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Göttingen 37077, Germany;2. Bourn Hall Clinic, High Street, Cambridge CB23 2TN, UK;3. DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, Copenhagen DK-2200, Denmark;4. Kinderwunschzentrum, Kasseler Landstraße 25A, Göttingen 37081, Germany
Abstract:
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  • Keywords:Corresponding author  kinetochore  meiosis  oocyte  aging  human  centromere  maternal age effect  cohesion  Trim-Away  aneuploidy
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