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Ornithine decarboxylase and polyamines in the resumption of cycling by diluted and reoxygenated mammalian cells |
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| Authors: | C. R. Kehe J. W. Harris |
| Affiliation: | Laboratory of Radiobiology, University of California, San Francisco, CA 94143, USA |
| Abstract: | Plateau-phase V79 Chinese hamster cells induced to reenter the proliferative cell cycle from G1/G0 by dilution in fresh medium showed an early increase in ornithine decarboxylase (ODC) followed by increases in some polyamines and in DNA synthesis. In contrast, cells accumulated in G1/G0 by growth in extreme hypoxia for 60 h and induced to recycle by reoxygenation did not respond with early increases in either ODC or polyamines. |
| Keywords: | Reprint requests should be addressed to Dr J. W. Harris Department of Radiation Oncology HSE 1666 University of California San Francisco CA 94143 USA. |
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