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Antioxidant activities of polysaccharides from Lentinus edodes and their significance for disease prevention |
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| Authors: | Chen Huoliang Ju Ying Li Junjie Yu Min |
| Institution: | a School of Military Preventive Medicine, Fourth Military Medical University, Xi’an 710032, China b Tangdu Hospital, Fourth Military Medical University, Xi’an 710032, China c Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China |
| Abstract: | The crude polysaccharide (LEP) was extracted by hot water from the fruiting bodies of Lentinus edodes, and further purified by DEAE-cellulose and Sepharose CL-6B chromatography, giving three polysaccharide fractions coded as LEPA1, LEPB1 and LEPC1. In this study, their chemical and physical characteristics of polysaccharide fractions and antioxidant capacities, including scavenging activity against hydroxyl radicals, superoxide radicals and Fe2+-chelating ability, were valuated. The results showed that LEPC1 exhibited significantly antioxidant activity at a concentration-dependent manner. Therefore these results indicated that the water-extractable polysaccharide fraction was a potent antioxidant and could be developed to be new health medicine for fighting against various human diseases. |
| Keywords: | Lentinus edodes Polysaccharide Antioxidant activity Disease prevention |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |