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An Immunocompetent Mouse Model of Zika Virus Infection
Authors:Matthew J. Gorman  Elizabeth A. Caine  Konstantin Zaitsev  Matthew C. Begley  James Weger-Lucarelli  Melissa B. Uccellini  Shashank Tripathi  Juliet Morrison  Boyd L. Yount  Kenneth H. Dinnon  Claudia Rückert  Michael C. Young  Zhe Zhu  Shelly J. Robertson  Kristin L. McNally  Jing Ye  Bin Cao  Indira U. Mysorekar  Michael S. Diamond
Affiliation:1. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA;2. Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA;3. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA;4. Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA;5. The Center of Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA;6. Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA;7. Department of Epidemiology, University of North Caroline at Chapel Hill, Chapel Hill, NC, USA;8. Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, USA;9. Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA;10. Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA;11. Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA;12. Department of Medicine, Division of Regenerative Medicine, University of California, San Diego, School of Medicine, La Jolla, CA, USA;13. Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, USA;14. Computer Technologies Department, ITMO University, St. Petersburg, Russia
Abstract:
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  • Keywords:Zika virus  flavivirus  pathogenesis  interferon  RNA sequencing  immunity  transgenic mice  vertical transmission  pregnancy  infectious clone
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