A new set of BXD recombinant inbred lines from advanced intercross populations in mice |
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| Authors: | Jeremy?L?Peirce mailto:jlpeirce@princeton.edu" title=" jlpeirce@princeton.edu" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Lu?Lu,Jing?Gu,Lee?M?Silver,Robert?W?Williams |
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| Affiliation: | (1) Center for Neuroscience Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, 855 Monroe Avenue Memphis, 38163 Tennessee, USA;(2) Louis Thomas Laboratory Department of Molecular Biology, Washington Road Princeton University, 08544 Princeton, NJ, USA |
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| Abstract: | ![]()
Background Recombinant inbred (RI) strains are an important resource for mapping complex traits in many species. While large RI panels are available for Arabidopsis, maize, C. elegans, and Drosophila, mouse RI panels typically consist of fewer than 30 lines. This is a severe constraint on the power and precision of mapping efforts and greatly hampers analysis of epistatic interactions. |
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