1. Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX 75390-9039, USA;2. Sierra Sciences, Reno, NV 89502, USA
Abstract:
Highlights? Alternative splicing is a new target for telomerase inhibition/activation ? Elements deep within introns regulate human telomerase splicing ? These intronic elements contain both unusual short repeats and direct repeats ? A direct-repeat oligonucleotide modifies splicing of endogenous telomerase