1. Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK;2. MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK;3. Hematopoietic Stem Cell Laboratory, Lund Stem Cell Center, Lund University, Lund 22184, Sweden;4. Ludwig Institute for Cancer Research, Brussels B1200, Belgium;5. de Duve Institute, Université Catholique de Louvain, Brussels B1200, Belgium;6. Institute for Stem Cell Research, MRC Centre for Regenerative Medicine, University of Edinburgh, King’s Buildings, West Mains Road, Edinburgh EH93JQ, UK