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Transposon mutagenesis of Mb0100 at the ppe1-nrp locus in Mycobacterium bovis disrupts phthiocerol dimycocerosate (PDIM) and glycosylphenol-PDIM biosynthesis, producing an avirulent strain with vaccine properties at least equal to those of M. bovis BCG |
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| Authors: | Hotter Grant S Wards Barry J Mouat Pania Besra Gurdyal S Gomes Jessica Singh Monica Bassett Shalome Kawakami Pamela Wheeler Paul R de Lisle Geoffrey W Collins Desmond M |
| Affiliation: | AgResearch, Wallaceville Animal Research Centre, P.O. Box 40063, Upper Hutt, New Zealand. grant.hotter@agresearch.co.nz |
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| 本文献已被 PubMed 等数据库收录！ | |