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Transposon mutagenesis of Mb0100 at the ppe1-nrp locus in Mycobacterium bovis disrupts phthiocerol dimycocerosate (PDIM) and glycosylphenol-PDIM biosynthesis, producing an avirulent strain with vaccine properties at least equal to those of M. bovis BCG
Authors:Hotter Grant S  Wards Barry J  Mouat Pania  Besra Gurdyal S  Gomes Jessica  Singh Monica  Bassett Shalome  Kawakami Pamela  Wheeler Paul R  de Lisle Geoffrey W  Collins Desmond M
Institution:AgResearch, Wallaceville Animal Research Centre, P.O. Box 40063, Upper Hutt, New Zealand. grant.hotter@agresearch.co.nz
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