Genetic linkage relations of the sixth component of complement (C6) |
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| Authors: | J. H. Olving B. Olaisen T. Gedde-Dahl Jr. P. Teisberg |
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| Affiliation: | (1) Institute of Forensic Medicine, University of Oslo, Rettsmedisinsk Institutt, Rikshospitalet, Oslo 1, Norway;(2) Genetics Laboratory, Norsk Hydro's Institute for Cancer Research, Radiumhospitalet, Oslo, Norway;(3) Medical Department A, Rikshospitalet, Oslo, Norway |
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| Abstract: | Summary Linkage relations between the C6 and 33 other genetic marker loci have been analyzed in Norwegian pedigrees, including 114 matings with 388 informative children, by use of the MOSM computer program. No suggestion of linkage was found. Very close or close linkage ( <0.06) has been ruled out for males between C6 and the following 19 marker loci: GPT, HLA+Bf, Rh, C3, Hp, PGM
3, Km, Gm, Fy, Gc, AB0, Jk, GLO
1, K, MNSs, PTC, ACP
1, PGM
1 and Pi. For several of the relations even loose linkage is unlikely. |
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