Visualization of pseudogenes in intracellular bacteria reveals the different tracks to gene destruction |
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| Authors: | Hans-Henrik Fuxelius Alistair C Darby Nam-Huyk Cho Siv GE Andersson |
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| Affiliation: | 1.Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvägen 18C, S-752 36 Uppsala, Sweden;2.Department of Microbiology and Immunology, College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center and Bundang hospital, 28 Yongon-Dong, Chongno-Gu, Seoul 110-799, Republic of Korea;3.Vector Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK |
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| Abstract: | Background Pseudogenes reveal ancestral gene functions. Some obligate intracellular bacteria, such as Mycobacterium leprae and Rickettsia spp., carry substantial fractions of pseudogenes. Until recently, horizontal gene transfers were considered to be rare events in obligate host-associated bacteria. |
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