抗真菌肽研究进展

有害真菌已造成植物真菌病害、食物污染和人类真菌感染等问题,给人们的生活和生产带来极大危害,且其逐渐增加对抗真菌药物的耐药性,导致真菌防治日益困难.传统的合成类抗真菌药物具有药物残留和毒副作用,已不能满足需求,作为生物机体天然防御分子的抗真菌肽已成为应对真菌危害及耐药性的重要研究对象.抗真菌肽能够抑制有害真菌,具有高效、...

Advance in the Research of the Antifungal Peptides

The harmful fungi have caused plant fungal disease,food contamination and human fungal infection,which can bring great harm to people’s life and production.Moreover,the increasing resistance of harmful fungi to antifungal drugs has made them difficult to control.Due to the drug residues and the toxic effects,the traditional synthetic fungicides have been unable to meet the people’s needs.Antifungal peptides,as the natural defense molecules of living organisms,have become an important research object in response to fungal hazards and drug resistance.Antifungal peptides can inhibit the harmful fungi,and have the characteristics of high efficiency,broad spectrum and high safety.The unique antifungal mechanism of antifungal peptides can solve the problem of fungal drug resistance,which has gradually attracted people’s attention in fungi control.Based on this,this paper mainly analyzed and discussed the following aspects such as the harm of fungi,the source of antifungal peptides,the method of isolation and purification,the antifungal mechanism of antifungal peptides,etc.,aiming to provide a reference for the study of antifungal peptides.