Conducting metagenomic studies in microbiology and clinical research |
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Authors: | Martin Tiphaine C. Visconti Alessia Spector Tim D. Falchi Mario |
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Affiliation: | 1.Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK ;2.Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA ; |
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Abstract: |
Owing to the increased cost-effectiveness of high-throughput technologies, the number of studies focusing on the human microbiome and its connections to human health and disease has recently surged. However, best practices in microbiology and clinical research have yet to be clearly established. Here, we present an overview of the challenges and opportunities involved in conducting a metagenomic study, with a particular focus on data processing and analytical methods. |
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