Correlation between hydrophobicity sequence and accessibility sequence of membrane proteins |
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| Authors: | Xu Qiang |
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| Affiliation: | State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China. |
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| Abstract: | In this paper, we used correlation analysis to quantify the correlations between the hydrophobicity sequence and accessibility sequence of 26 alpha-helix bundle membrane proteins and 119 transmembrane helices. Statistical significances of these correlations were also assessed. A slightly positive correlation was found in the alpha-helix bundle membrane proteins due to the contribution of extra-membranous domains. No correlation was found in the transmembrane domains. |
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