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Profile analysis of 24-hours measurements of blood pressure
Authors:Hirotsu Chihiro  Ohta Eri  Hirose Nobuyoshi  Shimizu Kenichiro
Affiliation:Faculty of Science and Technology, Meisei University, Tokyo. hirotsu@ge.meisei-u.ac.jp
Abstract:
A method is proposed for classifying subjects according to their convex, flat, or concave change patterns of 24-hours blood pressure measurements. To obtain such a classification is useful for detecting subjects who show abnormal change patterns and giving them appropriate medical treatments. Therefore, an appropriate statistic is proposed for detecting a systematic change along the time axis, as well as a statistic with its inverse characteristic appropriate for evaluating the noise variation. The method is based on the ratio of those two types of statistics; it is verified to work well on real data, giving a classification of subjects into four types of subgroups: extreme dipper, dipper, nondipper, and inverted dipper. It also suggests that there might be an ultra-extreme dipper subgroup.
Keywords:Analysis of interaction    Classification    Convex and concave patterns    Multiple comparisons    Order-restricted inference
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