| 经皮激光汽化术联合杜仲腰痛丸治疗腰椎间盘突出症的效果观察 |
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| 引用本文： | 赵继荣,王国慧,赵 宁,慕向前,朱 宝.经皮激光汽化术联合杜仲腰痛丸治疗腰椎间盘突出症的效果观察[J].现代生物医学进展,2019,19(6):1095-1098. |
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| 作者姓名： | 赵继荣 王国慧 赵 宁 慕向前 朱 宝 |
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| 作者单位： | 甘肃省中医院脊柱骨二科;甘肃中医药大学;甘肃省中医院手外科 |
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| 基金项目： | 国家自然科学基金项目(81760877) |
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| 摘 要： | 目的:研究经皮激光汽化术联合杜仲腰痛丸治疗腰椎间盘突出症的临床效果。方法:选择2016年4月~2018年4月我院脊柱骨科收治的106例腰椎间盘突出症患者,随机分为两组。对照组单独采用经皮激光汽化术治疗,观察组联合口服杜仲腰痛丸治疗,每次8粒,每天3次。比较两组的治疗有效率,治疗前后的VAS评分、JOA评分,血清白介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)水平的改变情况。结果:治疗后,观察组的治疗有效率为88.68%(47/53),明显高于对照组73.58%(39/53)](P0.05)。两组治疗后的VAS评分值均较治疗前明显降低(P0.05),JOA评分值均较对照组明显升高(P0.05),且观察组VAS评分值明显低于对照组,JOA评分值显著高于对照组(P0.05)。两组治疗后的血清IL-1β、TNF-α水平均较治疗前明显降低(P0.05),且观察组血清IL-1β、TNF-α水平明显低于对照组(P0.05)。两组均未发生神经损伤和无椎间盘炎等并发症。结论:经皮激光汽化术联合杜仲腰痛丸治疗腰椎间盘突出症的临床效果明显优于单独采用经皮激光汽化术治疗,其可以显著改善患者的生活质量,降低疼痛程度,其作用机制可能与有降低患者血清炎症介质IL-1β、TNF-α的表达有关。
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| 关 键 词： | 经皮激光汽化术 杜仲腰痛丸 腰椎间盘突出症 临床疗效 |
| 收稿时间： | 2018/9/5 0:00:00 |
| 修稿时间： | 2018/9/30 0:00:00 |
Observation on the Effect of Percutaneous Laser Vaporization Combined with Duzhongyaotong Pill in the Treatment of Lumbar Disc Herniation |
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| ZHAO Ji-rong,WANG Guo-hui,ZHAO Ning,MU Xiang-qian and ZHU Bao.Observation on the Effect of Percutaneous Laser Vaporization Combined with Duzhongyaotong Pill in the Treatment of Lumbar Disc Herniation[J].Progress in Modern Biomedicine,2019,19(6):1095-1098. |
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| Authors: | ZHAO Ji-rong WANG Guo-hui ZHAO Ning MU Xiang-qian and ZHU Bao |
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| Institution: | Orthopedics Department, Gansu Provincial Hospital of traditional Chinese Medicine, Lanzhou, Gansu 730050, China,1 Orthopedics Department, Gansu Provincial Hospital of traditional Chinese Medicine, Lanzhou, Gansu 730050, China;2 Gansu University of traditional Chinese Medicine, Lanzhou, Gansu, 730050, China,Orthopedics Department, Gansu Provincial Hospital of traditional Chinese Medicine, Lanzhou, Gansu 730050, China,Hand surgery, Gansu Provincial Hospital of traditional Chinese Medicine, Lanzhou, Gansu 730050, China and Orthopedics Department, Gansu Provincial Hospital of traditional Chinese Medicine, Lanzhou, Gansu 730050, China |
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| Abstract: | |
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| Keywords: | Percutaneous laser vaporization Duzhongyaotong pill Lumbar intervertebral disc Clinical efficacy |
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