| 胰胆管造影术后发生胰腺炎的危险因素分析 |
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| 引用本文： | 李 燕,田 铸,徐梦林,翟 军,谢百发.胰胆管造影术后发生胰腺炎的危险因素分析[J].现代生物医学进展,2019,19(6):1078-1082. |
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| 作者姓名： | 李 燕 田 铸 徐梦林 翟 军 谢百发 |
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| 作者单位： | 陆军军医大学第一附属医院急救部 |
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| 基金项目： | 国家自然科学基金项目(81071537) |
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| 摘 要： | 目的:探讨经胰胆管造影术后患者发生胰腺炎的危险因素,以期为临床实践提供一定的参考依据。方法:回顾性分析2015年1月1日至2018年1月1日入住我院行胰胆管造影术的患者,根据纳入排除标准,分成胰腺炎组和非胰腺炎组,比较分析两组患者的性别、年龄、既往行内镜逆行性胰胆管造影术(endoscopic retrograde pancreatic cholangiography,ERCP)与否、ERCP次数、ERCP手术时间、胆道括约肌气囊扩张术、插管困难等因素和血清炎症因子TNF-α、IL-1、IL-6、IL-10的表达情况。结果:研究共纳入1891例患者,并发胰腺炎者124例(6.55%),非胰腺炎患者1767例。性别、年龄、既往行ERCP、ERCP次数、ERCP手术时间、胆道括约肌气囊扩张术、插管困难均为胰腺炎发生的危险因素,且ERCP手术时间和胆道括约肌气囊扩张术是为并发胰腺炎的独立危险因素。ERCP术后胰腺炎组血清TNF-α、IL-1、IL-6、IL-10的表达水平均显著高于非胰腺炎组(P0.05)。结论:ERCP手术时间、胆道括约肌气囊扩张术及高血清炎症因子水平可能是并发胰腺炎的独立危险因素。
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| 关 键 词： | 胰胆管造影术 胰腺炎 危险因素 炎症因子 |
| 收稿时间： | 2018/8/10 0:00:00 |
| 修稿时间： | 2018/8/31 0:00:00 |
Analysis of the Risk Factors for Pancreatitis after Cholangiopancreatography |
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| LI Yan,TIAN Zhu,XU Meng-lin,ZHAI Jun and XIE Bai-fa.Analysis of the Risk Factors for Pancreatitis after Cholangiopancreatography[J].Progress in Modern Biomedicine,2019,19(6):1078-1082. |
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| Authors: | LI Yan TIAN Zhu XU Meng-lin ZHAI Jun and XIE Bai-fa |
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| Institution: | Department of emergency, Southwest Hospital in Third Military Medical University, Chongqing, 400038, China,Department of emergency, Southwest Hospital in Third Military Medical University, Chongqing, 400038, China,Department of emergency, Southwest Hospital in Third Military Medical University, Chongqing, 400038, China,Department of emergency, Southwest Hospital in Third Military Medical University, Chongqing, 400038, China and Department of emergency, Southwest Hospital in Third Military Medical University, Chongqing, 400038, China |
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| Abstract: | |
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| Keywords: | Cholangiopancreatography Pancreatitis Risk factors Inflammatory factors |
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